En bref
- Grade universitaire offert : Doctorat en philosophie (Ph.D.)
- Option de statut d’inscription : Temps complet
- Langues d’enseignement :
- Français
- Anglais
Note : Presque tous les cours de ce programme sont offerts en anglais.
- Programme principal : Ph.D. Chimie
- Spécialisation pluridisciplinaire : Toxicologie chimique et environnementale
- Option d’études (durée prévue du programme) :
- avec thèse (12 trimestres à temps complet, soit 48 mois consécutifs)
- Unités scolaires : Faculté des sciences, Département de chimie et sciences biomoléculaires, Institut de chimie d’Ottawa-Carleton.
Description du programme
Fondé en 1981, l’Institut de chimie d’Ottawa-Carleton (ICOC) combine les ressources en recherche de l’Université d'Ottawa et de la Carleton University. L’Institut offre des programmes d’études supérieures de maîtrise (M.Sc.) et de doctorat (Ph.D.) en chimie.
Les installations de recherche sont partagées entre les deux campus. Les étudiants ont accès aux cours, à l’équipement et aux professeurs des deux universités mais doivent s’inscrire à l’université d’attache de leur directeur de thèse.
L’Institut participe au programme pluridisciplinaire en science, société et politique publique, au niveau de la maîtrise et en toxicologie chimique et environnementale, au niveau de la maîtrise et du doctorat.
En apprendre plus sur ce programme
Description du programme pluridisciplinaire
La toxicologie est l'étude des effets des substances toxiques organiques ou inorganiques, synthétiques ou naturelles sur les systèmes vivants. La toxicologie environnementale englobe l’étude des effets, aux niveaux des populations et des communautés, de différents aspects des substances toxiques comme leur transport chimique, leur devenir, leur persistance, et leur accumulation biologique. Contrairement au chercheur qui se concentre sur un domaine particulier, le toxicologue contemporain doit prendre en considération les recherches effectuées dans d'autres domaines, ce qui sous-entend une compréhension des principes de base d'autres disciplines. Pour répondre à ce défi, l'Université d'Ottawa et Carleton University offrent un programme pluridisciplinaire conjoint menant à l'obtention d'une maîtrise ès sciences ou d’un doctorat avec spécialisation en toxicologie chimique et environnementale.
Le programme pluridisciplinaire d'Ottawa-Carleton en toxicologie chimique et environnementale vient élargir la formation et accroître les occasions de recherche par voie des instituts partenaires du programme.
Principaux domaines de recherche
- La chimie organique
- La chimie inorganique
- La chimie analytique
- La chimie théorique
- La chimie biologique
- La chimie physique
Autres programmes offerts dans la même discipline ou dans une discipline connexe
- Maîtrise ès sciences Chimie (M.Sc.)
- Maîtrise ès sciences Chimie Spécialisation en science, société et politique publique (M.Sc.)
- Maîtrise ès sciences Chimie Spécialisation en toxicologie chimique et environnementale (M.Sc.)
- Doctorat en philosophie Chimie (Ph.D.)
Coût et financement
- Frais reliés aux études :
Le montant estimé des droits universitaires de ce programme est disponible sous la section Financer vos études.
Les étudiants internationaux inscrits à un programme d'études en français peuvent bénéficier d'une exonération partielle des droits de scolarité.
- Pour des renseignements sur les moyens de financer vos études supérieures, veuillez consulter la section Bourses et appui financier.
Notes
- Les programmes sont régis par les règlements académiques en vigueur pour les études supérieures des deux universités.
- Conformément au règlement de l’Université d’Ottawa, les travaux, les examens, les mémoires, et les thèses peuvent être complétés en français ou en anglais.
- Les activités de recherche peuvent se dérouler soit en anglais, soit en français, ou encore dans les deux langues en fonction de la langue principale du professeur et des membres du groupe.
Coordonnées du programme
Bureau des études supérieures, Faculté des sciences
30 Marie-Curie, Pavillon Gendron, pièce 181
Ottawa, Ontario, Canada
K1N 6N5
Tél. : 613-562-5800 x 3145
Courriel : gradsci@uottawa.ca
Twitter | Faculté des sciences
Facebook | Faculté des sciences
Pour connaître les renseignements à jour concernant les dates limites, les tests de langues et autres exigences d'admission, consultez la page des exigences particulières.
Pour être admissible, vous devez :
- Être titulaire d’une maîtrise en chimie (ou l’équivalent) avec une moyenne minimale d'admission de 75 % (B+).
Note : Les candidats internationaux doivent vérifier les équivalences d’admission pour le diplôme obtenu dans leur pays de provenance.
- Avoir un bon rendement scolaire tel que démontré par les relevés de notes officiels, les rapports de recherche, les résumés ou d’autres documents à l’appui démontrant une expérience de recherche.
- Satisfaire aux exigences de financement.
Note : Les étudiants étrangers doivent fournir une preuve de financement, c'est-à-dire une allocation d'un superviseur et une combinaison de bourses et/ou de fonds en fiducie.
- Identifier au moins un professeur prêt à diriger votre recherche et votre thèse.
- Il est recommandé de communiquer avec le directeur de thèse dès que possible.
- Pour pouvoir vous inscrire, vous devez faire accepter votre candidature par un directeur de thèse.
- Le nom du professeur est requis lors de la demande d’admission.
- Le choix du professeur détermine le campus où il faut poursuivre la recherche et ce sera aussi l'université qui octroie le diplôme.
- Être parrainé par un professeur de la spécialisation pluridisciplinaire, habituellement son directeur de recherche, qui a une nomination régulière, ou une double affectation, ou une nomination à titre de professeur auxiliaire dans le programme principal.
- Satisfaire aux exigences additionnelles suivantes :
Exigences linguistiques
Les candidats doivent comprendre, écrire et parler couramment la langue d'enseignement, soit le français, soit l'anglais, du programme dans lequel ils veulent s'inscrire. Une preuve de compétence linguistique peut être requise.
Ceux dont la langue maternelle n'est ni le français ni l'anglais doivent fournir une preuve de compétence dans la langue d'enseignement.
Note : Les coûts des tests de compétences linguistiques devront être assumés par le candidat.
Notes
- Les conditions d'admission décrites ci-dessus représentent des exigences minimales et ne garantissent pas l'admission au programme.
- Les admissions sont régies par les règlements académiques en vigueur pour les études supérieures et par les règlements généraux de l'Institut de chimie d’Ottawa-Carleton (ICOC).
- Il faut indiquer dans la demande initiale d'admission au programme de doctorat en Chimie qu'on veut être admis dans le programme pluridisciplinaire en toxicologie chimique et environnementale. Pour être admis, le candidat doit être admis au préalable au programme participant principal.
Passage accéléré de la maîtrise au doctorat
Les étudiants inscrits au programme de maîtrise en Chimie à l’Université d’Ottawa ont la possibilité de passer directement au programme de doctorat sans avoir à rédiger la thèse de maîtrise dans la mesure où les conditions suivantes sont remplies :
- Réussite de quatre cours d’études supérieures (6 crédits) avec une note minimale de A- dans chacun.
- Progrès satisfaisant dans le programme de recherche.
- Recommandation écrite du directeur de thèse ainsi que des membres du comité de thèse.
- Approbation du comité des études supérieures.
Notes :
- Le passage doit avoir lieu dans les seize mois qui suivent l’inscription initiale à la maîtrise.
- Les conditions minimales de moyenne d’admission au programme de doctorat doivent également être rencontrées.
Doctorat avec spécialisation pluridisciplinaire
Les exigences de ce programme ont été modifiées. Les exigences antérieures peuvent être consultées dans les annuaires 2025-2026.
L’étudiant doit satisfaire aux exigences de son programme principal et à celles du programme pluridisciplinaire. Les crédits complétés pour la spécialisation comptent aussi dans les exigences du programme principal.
Selon l’expérience antérieure de l’étudiant, le Département peut imposer des cours additionnels.
Les exigences à remplir sont les suivantes :
| Code | Title | crédits |
|---|---|---|
| Cours obligatoires : | ||
| 3 crédits de cours parmi : | 3 crédits | |
| Principles of Toxicology | ||
| Ecotoxicology | ||
| 3 crédits de cours optionnels en chimie (CHM) de niveau gradué 1 | 3 crédits | |
| Séminaires : | ||
| CHM 8257 | PhD Seminar | 1 crédit |
| TOX 9105 | Seminar in Toxicology 2 | 3 crédits |
| Examen de synthèse : | ||
| CHM 9998 | Examen général de doctorat 3 | |
| Projet de thèse : | ||
| CHM 8958 | Projet de recherche | |
| Thèse : | ||
| THD 9999 | Thèse de doctorat 4, 5 | |
Note(s)
- 1
Les crédits de cours optionnels peuvent aussi être choisis dans des disciplines connexes approuvés par le Département de chimie.
- 2
Si le séminaire TOX 9105 a déjà été suivi dans le contexte de la spécialisation au niveau de la maîtrise, cette exigence ne s’applique pas.
- 3
L'examen de synthèse doit être fait dans les douze mois suivant la première inscription au programme.
- 4
Présentation et soutenance réussie d'une thèse en toxicologie basée sur des travaux de recherche originaux effectués sous la direction d'un membre du corps professoral participant au programme conjoint en toxicologie chimique et environnementale.
- 5
L’étudiant est responsable de s’assurer de rencontrer les exigences relatives à la thèse.
Passage accéléré de la maîtrise au doctorat
Suite au passage accéléré, il faut remplir toutes les exigences du doctorat : réussite d’un nombre total de 12 crédits de cours au niveau supérieur (M.Sc.+Ph.D.); réussite du séminaire (CHM 8257); réussite de l’examen de synthèse (CHM 9998); réussite du projet de thèse (CHM 8958); et réussite de la thèse (THD 9999).
Exigences minimales
La note de passage dans tous les cours est de B.
La recherche à l’Université d’Ottawa
Située au cœur de la capitale du Canada, à quelques pas de la colline du Parlement, l’Université d’Ottawa se classe parmi les 10 meilleures universités de recherche au Canada. Notre recherche est fondée sur l’excellence, la pertinence et l’impact et s'effectue dans un esprit d'équité, de diversité et d'inclusion.
Notre communauté de recherche se développe dans quatre axes stratégiques :
- Créer un environnement durable,
- Promouvoir des sociétés justes,
- Façonner le monde numérique
- Favoriser santé et bien-être tout au long de la vie.
Qu'il s'agisse de faire progresser les solutions en matière de soins de santé ou de relever des défis mondiaux comme les changements climatiques, les chercheurs de l'Université d'Ottawa sont à l'avant-garde de l'innovation et apportent des contributions importantes à la société et au-delà.
La recherche à la Faculté des sciences
La Faculté des sciences est devenue un centre d’excellence en recherche grâce à ses professeurs de renommée mondiale ainsi qu’à ses programmes et infrastructures en biologie, chimie, sciences de la Terre, physique, mathématiques et statistiques.
L’excellence de ses 140 professeurs de stature internationale, de ses 400 étudiants aux cycles supérieurs et de ses douzaines de chercheurs postdoctoraux et scientifiques invités a fait de la Faculté des sciences l’une des plus productives en recherche au Canada. Nos professeurs se sont mérités plusieurs reconnaissances nationales et internationales dont trois récipiendaires de la médaille d’or Gerhard-Herzberg du CRSNG et plusieurs élections à la Société royale du Canada.
La Faculté des sciences a bénéficié d’investissements majeurs en infrastructure qui ont permis de développer des plateformes de recherche et de fournir des capacités de recherche à la fine pointe dans les domaines de la catalyse, la chimie expérimentale et quantitative, les contaminants environnementaux, la résonnance magnétique nucléaire, l’analyse d’isotopes, la biologie moléculaire et génomique, la spectrométrie/diffractométrie à rayons-X, la spectrométrie de masse, la physiologie et génétique des organismes aquatiques et la photonique. De plus, la Faculté des sciences est affiliée au Centre de recherche mathématiques (CRM) de l'Université de Montréal et à l'Institut Fields de recherche en sciences mathématiques, offrant un environnement unique pour la recherche en mathématiques.
Pour d’autres informations, veuillez consulter la liste des membres du corps professoral et leurs domaines de recherche sur Uniweb.
IMPORTANT : Les candidats et les étudiants à la recherche de professeurs pour superviser leur thèse ou leur projet de recherche peuvent aussi consulter le site Web de la faculté ou du département du programme de leur choix. La plateforme Uniweb n’est pas représentative de l’ensemble du corps professoral autorisé à diriger des projets de recherche à l’Université d’Ottawa.
Tous les cours ne sont pas nécessairement offerts chaque année. Les cours sont offerts dans la langue dans laquelle ils sont décrits.
Un cours de 3 crédits à l’Université d’Ottawa correspond à un cours de 0,5 crédit à la Carleton University.
CHM 5105 Radiochemistry (3 units)
A study of nuclear stability and decay; chemical studies of nuclear phenomena. Application of radioactivity.
Course Component: Lecture
Permission of the Department is required.
CHM 5108 Surface Chemistry and Nanostructures (3 units)
Surface structure, thermodynamics and kinetics, specifically regarding adsorption/desorption and high vacuum models. Nanoscale structures and their formation, reactivity and characterization. Thin films, carbon nanotubes, self-assembled monolayers and supramolecular aggregates. This course is equivalent to CHEM 5108 at Carleton University
Course Component: Lecture
CHM 5109 Advanced Applications in Mass Spectrometry (3 units)
Detailed breakdown of the physical, electrical and chemical operation of mass spectrometers. Applications in MS ranging from the analysis of small molecules to large biological macromolecules. Descriptions of the use of mass spectrometry in industry as well as commercial opportunities in the field. This course is equivalent to CHEM 5109 at Carleton University.
Course Component: Lecture
CHM 5206 Physical Methods of Nanotechnology (3 units)
An overview of methods used in nanotechnology. Principles of scanning probe techniques ranging from surface physics to biology. State of the art methods to create nanostructures for future applications in areas such as nanolithography, nanoelectronics, nano-optics, data storage and bio-analytical nanosystems. This course is equivalent to CHEM 5206 at Carleton University.
Course Component: Lecture
CHM 5207 Macromolecular Nanotechnology (1.5 units)
Fundamentals of synthetic macromolecules related to nanoscale phenomena. Challenges and opportunities associated with polymers on the nanoscale. Topics include molecular recognition, self-assembled nanostructures, functional nanomaterials, amphiphilic architectures, nanocomposites, and nanomachines. Applications to sensing, drug delivery, and polymer based devices. This course is equivalent to CHEM 5207 at Carleton University.
Course Component: Lecture
CHM 5208 Bio Macromolecular Nanotechnology (1.5 units)
Fundamentals of biological macromolecules related to nanoscale phenomena. Challenges and opportunities associated with natural polymers on the nanoscale. Topics include molecular recognition, self-assembled nanostructures, scaffolds and templates, functional nanomaterials, amphiphilic architectures, nanocomposites, and nanomachines. Applications to sensing, biomaterials, drug delivery, and devices. This course is equivalent to CHEM 5208 at Carleton University.
Course Component: Lecture
CHM 5606 Environmental Chemistry and Toxicology (1.5 crédits)
Overview of environmental chemistry and toxicology principles including chemical sources, fate, and effects in the environment. Examining organic reactions occurring in abiotic environments and biological systems, and study aspects of toxicant disposition and biotransformation. Emphasis on contemporary problems in human health and the environment. This course is equivalent to CHEM 5606 at Carleton University
Volet : Cours magistral
CHM 8104 Scientific Data Processing and Evaluation (3 units)
Optimization of scientific measurements, calibration, uni-variate and multi-variate analysis of scientific data, 'intelligent' spreadsheets for scientific data processing and presentation, noise reduction using spreadsheets, correction for signal drifts; examples from chemistry, spectroscopy and other scientific disciplines. This course is equivalent to CHEM 5904 at Carleton University.
Course Component: Lecture
CHM 8126 Bioorganic Chemistry (3 units)
Overview of recent developments in the mechanistic understanding of selected enzyme-catalyzed reactions. Topics include Cytochrome P450, methane monooxygenase, biotin and lipoic acid biosynthesis, methyl transfer, Vitamin B12, lipoxygenase, prostaglandin synthase; etc. Emphasis will be placed on biotransformations which are relatively poorly understood from a mechanistic point of view. This course is equivalent to CHEM 5303 at Carleton University.
Course Component: Lecture
CHM 8134 Spectroscopy for Organic Chemists (3 units)
Analysis of proton NMR spectra. Fourier transform 13C NMR, strategies for structure elucidation, relaxation times, two-dimensional NMR. Aspects of mass spectrometry. This course is equivalent to CHEM 5407 at Carleton University.
Course Component: Lecture
CHM 8150 Special Topics in Molecular Spectroscopy (3 units)
Topics of current interest in molecular spectroscopy. In past years, the following areas have been covered: electronic spectra of diatomic and triatomic molecules and their interpretation using molecular orbital diagrams; Raman and resonance Raman spectroscopy; symmetry aspects of vibrational and electronic levels of ions and molecules in solids in the presence of weak and strong resonant laser radiation. This course is equivalent to CHEM 5009 at Carleton University.
Course Component: Lecture
CHM 8158 Directed Special Studies (3 units)
Under unusual circumstances and with the recommendation of the research supervisor, it is possible to engage in a directed study on a topic of particular value to the student. This may also be used for unit if there are insufficient course offerings in a particular field of chemistry. This course is equivalent to CHEM 5900 at Carleton University.
Course Component: Lecture
CHM 8164 Organic Polymer Chemistry (3 units)
Basic principles of industrial and synthetic polymers. Polymerization and polymer characterization. Selected topics to cover some important polymers with emphasis on the synthesis, commodity plastics, engineering thermoplastics and specialty polymers. Students should have a basic knowledge of organic reaction mechanisms and stereochemistry. This course is equivalent to CHEM 5406 at Carleton University.
Course Component: Lecture
Prerequisites: CHM 3120, CHM 4120, CHM 4125, equivalent. or A basic knowledge of organic reaction mechanisms and stereochemistry.
CHM 8165 Advanced Protein Engineering (3 units)
Overview of recent developments in the conception and design of proteins with novel structures and functions. Topics include rational and computational design, ancestral protein reconstruction, and directed evolution of proteins.
Course Component: Lecture
CHM 8173 Introduction to Molecular Simulation and Statistical Mechanics (Part A) (1.5 units)
A practical introduction to modern molecular simulation techniques widely used as tools in chemical research. Classical molecular dynamics and Monte Carlo simulations methods are discussed. The necessary statistical mechanics required to understand and properly interpret the molecular simulations and link the results to measured bulk properties are introduced. An introduction to modern scientific computing environments and the Linux operating system is also provided. This course is equivalent to CHEM 5114 at Carleton University.
Course Component: Lecture
CHM 8174 Stereoselective Synthesis (1.5 units)
Fundamentals of stereoselective synthesis and catalysis, including conformational analysis, substrate and catalyst control. Includes the use of allylic, chiral auxiliaries, directed reactions and chiral catalysts. This course is equivalent to CHM 5113 at Carleton University.
Course Component: Lecture
CHM 8175 Introduction to Molecular Simulation and Statistical Mechanics (Part B) (1.5 units)
A practical introduction to modern molecular simulation techniques widely used as tools in chemical research. Classical molecular dynamics and Monte Carlo simulations methods are discussed. The necessary statistical mechanics required to understand and properly interpret the molecular simulations and link the results to measured bulk properties are introduced. An introduction to modern scientific computing environments and the Linux operating system is also provided. This course is equivalent to CHEM 5115 at Carleton University.
Course Component: Lecture
CHM 8176 Chemistry Education and Chemistry Education Research (1.5 units)
Overview of key areas of chemistry education, including theories of learning, aligning intended outcomes with course activities and assessment, and troublesome areas of learning and teaching in chemistry. Key educational research areas are addressed, including types evidence, research methods, and central publications. This course is equivalent to CHEM 5110 at Carleton University
Course Component: Lecture
CHM 8180 Directed Special Studies (1.5 units)
Under unusual circumstances and with the recommendation of the research supervisor, it is possible to engage in a directing study on a topic of particular value to the student. This may also be used for unit if there are insufficient course offerings in a particular field of chemistry. This course is equivalent to CHEM 5900 at Carleton University.
Course Component: Lecture
CHM 8181 Chemical Physics of Electron-Molecule Collisions (3 units)
Basic classical scattering theory and quantum mechanical scattering theory. Experimental aspects, such as electron optics, electron gun fundamentals, energy analyzers and electron detectors. Applications to the understanding of the chemistry of materials. This course is equivalent to CHEM 5101 at Carleton University.
Course Component: Lecture
CHM 8256 Seminar I (1 unit)
A seminar course in which students are required to present a seminar on a topic not related to their research project. In addition, students are required to attend the seminar of their fellow classmates and actively participate in the discussion following the seminar. This course is equivalent to CHEM 5801 at Carleton University.
Course Component: Seminar
CHM 8257 PhD Seminar (1 unit)
Students are required to present a seminar on their PhD research project in the context of a Departmental Seminar. The seminar should be done towards the end of the degree, but before thesis submission. Students must register and complete this requirement no later than in term 12 of the PhD program or earlier. This course is equivalent to CHEM 5802 at Carleton University.
Course Component: Seminar
CHM 8301 Analytical Mass Spectrometry (1.5 units)
The principles of ion sources and mass spectrometers will be described, together with their applications to problems in chemistry and biochemistry. Introduction to the chemistry gaseous ions. Ion optics. Special emphasis on interpreting mass spectra. This course is equivalent to CHEM 5001 at Carleton University.
Course Component: Lecture
CHM 8302 Advanced Topics in Inorganic Chemistry (1.5 units)
Topics of current interest in inorganic chemistry. Variable content from year to year. This course is equivalent to CHEM 5902 at Carleton University.
Course Component: Lecture
CHM 8303 Descriptive Organometallic Chemistry (1.5 units)
Review of basic concepts of M-C bonds and of the preparation and reactivity of transition and non-transition metal organometallic species. Brief discussion of the most important catalytic processes (e.g. Ziegler-Natta, Fisher-Tropsch, catalytic hydrogenation and hydroformilation). This course is equivalent to CHEM 5204 at Carleton University.
Course Component: Lecture
CHM 8304 Advanced Topics in Organic Chemistry (1.5 units)
Topics of current interest in organic chemistry. Variable content from year to year. This course is equivalent to CHEM 5901 at Carleton University.
Course Component: Lecture
CHM 8308 Multinuclear Magnetic Resonance Spectroscopy (1.5 units)
Principles of Nuclear Magnetic Resonance (NMR). Study of NMR parameters: chemical shift, spin-spin coupling, electric quadrupole coupling, spin-spin and spin-lattice relaxation rates. NMR and the periodic table. Dynamic NMR. Applications in chemistry and biochemistry. Fourier Transform technique. Pulse sequences. Basic principles and applications of two-dimensional NMR. This course is equivalent to CHEM 5002 at Carleton University.
Course Component: Lecture
CHM 8309 Advanced Topics in Physical (1.5 units)
Topics of current interest in physical/theoretical chemistry. Variable content from year to year. This course is equivalent to CHEM 5903 at Carleton University.
Course Component: Lecture
CHM 8310 Introduction to Photochemistry (1.5 units)
Basic principles of photochemistry including selection rules, energy transfer processes and the properties of excited state reactions. Lasers and their applications to measurements of the dynamics of elementary reactions. This course is equivalent to CHEM 5007 at Carleton University.
Course Component: Lecture
CHM 8311 Advanced and Applied Photochemistry (1.5 units)
Photochemical reactions of small molecules and their relationship to atmospheric chemistry. Production and detection of reactive species. Photolysis. Multiphoton absorption. This course is equivalent to CHEM 5008 at Carleton University.
Course Component: Lecture
Prerequisite: CHM 8310
CHM 8314 Surface Chemistry Aspects of Electrochemical Science (1.5 units)
Introduction to electrode processes and electrolysis. Potential differences at interfaces. Characterization of the electrical double layer. Dipole orientation effects, charge-transfer in adsorbed layers, electrochemical origins of surface science concepts. Theory of electron transfer, electrode kinetics, electrocatalysis. This course is equivalent to CHEM 5504 at Carleton University.
Course Component: Lecture
CHM 8315 Electrochemical Surface Science (1.5 units)
Introduction to advanced in-situ techniques in electrochemistry: Scanning probe microscopy, Raman, infrared and laser spectroscopy. This course is equivalent to CHEM 5505 at Carleton University.
Course Component: Lecture
CHM 8316 Surface Chemistry (1.5 units)
Adsorption phenomena and isotherms, surface areas of solids. Modern techniques in surface chemistry and surface science such as electron diffraction, Auger electron spectroscopy, photoelectron spectroscopy, electron energy loss spectroscopy, infrared and Raman spectroscopy. Current new techniques. This course is equivalent to CHEM 5506 at Carleton University.
Course Component: Lecture
CHM 8319 Total Syntheses (1.5 units)
Discussion on philosophy and strategy development for complex syntheses, along with modern reagents and reactions that have shortened classical routes and lead to more efficient and atom economy. This course is equivalent to CHEM 5403 at Carleton University.
Course Component: Lecture
CHM 8320 Pericyclic and Stereoelectronic Effects (1.5 units)
Pericyclic reactions, facial selectivity, stereoelectronic effects in carbohydrates and related acetal cleavage. Applications to complex synthetic problems. This course is equivalent to CHEM 5405 at Carleton University.
Course Component: Lecture
CHM 8321 Solid State Chemistry (1.5 units)
Thermodynamic and kinetic aspects of solid state synthesis. Characterization of solids. Chemical and physical properties of solids that may include aspects of intercalation reactions, ionic conductors, glasses, electronic, magnetic optical and physical/mechanical properties. This course is equivalent to CHEM 5201 at Carleton University.
Course Component: Lecture
CHM 8322 Topics in Coordination Chemistry (1.5 units)
Brief introduction to basic concepts in coordination chemistry. Topics to include the following: carbon dioxide fixation, dinitrogen fixation, activation, olefin metathesis, nature of the M-M bond. This course is equivalent to CHEM 5203 at Carleton University.
Course Component: Lecture
CHM 8323 Quantum Mechanical Methods - Theory (1.5 units)
Examination of the theory behind quantum mechanical methods (HF, MP2, CI, DFT). Semi-empirical. This course is equivalent to CHEM 5600 at Carleton University.
Course Component: Lecture
CHM 8324 Quantum Mechanical Methods - Applications (1.5 units)
Practical applications of methods taught in CHM 8323 such as thermochemistry, reaction pathway moeling, structure predictions. This course is equivalent to CHEM 5601 at Carleton University.
Course Component: Lecture
CHM 8325 Solid State Nmr Spectroscopy (1.5 units)
Brief introduction to solid state NMR spectroscopy. Topics include dipolar coupling interactions, chemical shielding anisotropy, the quadrupolar interaction and averaging techniques such as magic angle spinning. This course is equivalent to CHEM 5003 at Carleton University.
Course Component: Lecture
CHM 8326 Nmr Spectroscopy (1.5 units)
Advanced NMR techniques for both proton and carbon spectra, various decoupling and related experiments. Interpretation of NOSY, COSY and related data. This course is equivalent to CHEM 5004 at Carleton University.
Course Component: Lecture
CHM 8327 Physical Organic Chemistry (1.5 units)
Transition state theory, experimental kinetics and thermodynamics, isotope effects, Linear Free Energy Relationships (LFERs), catalysis and Reaction Profile Kinetic Analysis (RPKA). This course is equivalent to CHEM 5005 at Carleton University
Course Component: Lecture
CHM 8328 Applications of Organometallic Chemistry to Synthesis (1.5 units)
Study of organometallic methods, many of which have become catalytic and involve metals such as Cu, Pd, Pt, Mo, Cr, Ru. Various applications to be discussed including Stille coupling, Heck reaction, ring closing metathesis. This course is equivalent to CHEM 5401 at Carleton University.
Course Component: Lecture
CHM 8329 Medicinal Chemistry (1.5 units)
Preparation of drugs, their mode of action, their use in treating of disease. Evolution of medicine due to chemistry. Discussion of metabolic pathways and their modification to control and/or circumvent disease. This course is equivalent to CHEM 5402 at Carleton University.
Course Component: Lecture
CHM 8330 Heterocyclic Chemistry (1.5 units)
Properties of heterocycles. Synthesis and reactivity of heterocyclic systems, with examples relevant to the synthesis of pharmaceuticals and natural products. Includes metal-catalysed reactions. This course is equivalent to CHEM 5120 at Carleton University.
Course Component: Lecture
CHM 8331 Physical Chemistry of Biological Macromolecules (1.5 units)
Focus on how the application of physical techniques, normally applied to small molecules, can be used to study macromolecular structure and function of DNA and proteins. Examples of applications to include: kinetics, electrochemistry, equilibria phemonmena (thermodynamics). This course is equivalent to CHEM 5300 at Carleton University.
Course Component: Lecture
CHM 8332 Electrochemical Phenomena in Biological Systems (1.5 units)
Description of theory accounting for the generation of membrane potentials. Application to the generation of nerve impulses. This course is equivalent to CHEM 5301 at Carleton University.
Course Component: Lecture
CHM 8333 Surface Phenomena in Biological Systems (1.5 units)
Description of theory of surface tension phenomena in aqueous systems. Discussion of effects of cell and macromolecular structures in biological systems. This course is equivalent to CHEM 5302 at Carleton University.
Course Component: Lecture
CHM 8334 Novel Organic and Inorganic Molecules and Radicals (1.5 units)
Topics to include neutralization-reionization techniques as well as flash pyrolysis and matrix isolation studies. This course is equivalent to CHEM 5009 at Carleton University.
Course Component: Lecture
CHM 8336 Non-Equilibrium Kinetics (1.5 units)
Gas phase chemical kinetics of elementary and complex reaction mechanisms, as seen from a microscopic viewpoint. Unimolecular and bimolecular reactions under conditions of non-Boltzmann energy distributions. Consequences for combustion and atmospheric chemistry, as well as for fundamental kinetics. This course is equivalent to CHEM 5604 at Carleton University.
Course Component: Lecture
CHM 8337 Non-Linear Chemical Kinetics (1.5 units)
Principles of non-linear dynamics as applied to very complex chemical reaction mechanisms containing feed-back processes. Monotonic, oscillatory, and chaotic dependence of concentrations on time. Gas phase and liquid phase reactions. This course is equivalent to CHEM 5605 at Carleton University.
Course Component: Lecture
CHM 8338 Unimolecular Reaction Dynamics: Experiment and Theory (1.5 units)
Presentation of the theoretical models that have been developed for the understanding of unimolecular reactions, focussing on statistical theories such as RRKM theory. Experimental techniques for exploring the kinetics and mechanism of unimolecular reactions, including mass spectrometry, coincidence spectroscopy and ZEKE spectroscopy. This course is equivalent to CHEM 5100 at Carleton University.
Course Component: Lecture
CHM 8339 Heterogeneous Catalysis (1.5 units)
Principles of catalytic reactions and topics in modern applications of catalysis. Bonding of substrates on surfaces; cluster-surface analogy; ensemble requirements; mechanisms of catalysis on metal and metal oxide surfaces. This course is equivalent to CHEM 5105 at Carleton University.
Course Component: Lecture
CHM 8340 Organotransition Metal Catalysis: E-H Bond Activation (1.5 units)
Focus on the catalytic activation of E-H bonds by soluble organometallic complexes. Examples to include hydrogenation, hydrosilation and hydroboration catalysis, hydroamination and hydrophosphination. This course is equivalent to CHEM 5106 at Carleton University.
Course Component: Lecture
CHM 8341 Transition-Metal Catalyzed Polymerization (1.5 units)
Recent developments in polymerization catalysis via transition metal complexes, including insertion, metathesis, and atom-transfer polymerization. Brief overview of relevant concepts in polymer chemistry (e.g. molecular weight, polydispersity, living polymerization, the glass transition). This course is equivalent to CHEM 5107 at Carleton University.
Course Component: Lecture
CHM 8343 Chemistry of the Main Group Elements (1.5 units)
Fundamental and applied aspects of main group element chemistry. Topics may include non-metal chemistry, main group organometallic chemistry, application of main group element compounds to 3 uses of main group element compounds in synthesis. This course is equivalent to CHEM 5202 at Carleton University.
Course Component: Lecture
CHM 8344 Computational Approaches in Medicinal Chemistry (1.5 units)
Theory and application of methods used in the pharmaceutical industry including molecular mechanics. This course is equivalent to CHEM 5602 at Carleton University.
Course Component: Lecture
CHM 8345 Molecular Energy Transfer (1.5 units)
Principles of energy transfer during non-reactive molecular collisions as deduced from experiment and theory, mostly in the gas phase. Translational, rotational, vibrational and electronic energies are discussed. This course is equivalent to CHEM 5603 at Carleton University.
Course Component: Lecture
CHM 8346 Supercritical Fluids (1.5 units)
Fundamental and practical aspects of the uses of supercritical fluids in the chemistry laboratory. Thermodynamic treatment of high pressure multicomponent phase equilibria, transport properties, solubilities, supercritical fluid extraction and chromatography for analytical purposes, reactions in supercritical fluids, equipment considerations, new developments. This course is equivalent to CHEM 5102 at Carleton University.
Course Component: Lecture
CHM 8348 Analytical Instrumentation (1.5 units)
Principles of modern electronics, devices and instruments. Measurement of photonic and electrochemical signals. Conditioning of signals for feedback control and microcomputer interfacing. Computational data analysis techniques such as simplex optimization. Applications in chemical analysis include amperometric detector for capillary electrophoresis, and surface plasmon resonance immunosensor. This course is equivalent to CHEM 5500 at Carleton University.
Course Component: Lecture
CHM 8349 Free Radicals in Chemistry and Biology (1.5 units)
Oxidative stress induced by free radicals plays a significant role in most fatal and chronic diseases. The chemistry of bio-radicals will be described and related to pathobiological processes such as lipid peroxdiation and atherosclerosis, protein nitration and cross linking, and DNA scission. This course is equivalent to CHEM 5304 at Carleton University.
Course Component: Lecture
CHM 8352 Analytical Approach to Chemical Problems (1.5 units)
Case study of analytical approach to various chemical problems in agricultural, biochemical, environmental, food processing, industrial, pharmaceutical and material sciences. Analytical methods include capillary electrophoresis, chemiluminescence, Fourier transform infrared spectroscopy, inductively coupled plasma emission spectroscopy, mass spectrometry, biochemical sensors, and fiber optics for remote sensing. This course is equivalent to CHEM 5501 at Carleton University.
Course Component: Lecture
CHM 8353 Trace and Ultratrace Analytical Chemistry (3 units)
Criteria for evaluation and selection of analytical techniques and methods. Electroanalytical techniques. Simultaneous and sequential multielement determination. Atomic absorption, atomic emission and atomic fluorescence spectrometry, using optical spectrometric and mass-spectrometric determination. Applications of these techniques at trace and ultratrace levels in complex matrices. This course is equivalent to CHEM 5502 at Carleton University.
Course Component: Lecture
CHM 8355 Trace Elemental Analysis Using Inductively Coupled Plasma Emission (Icp-Es) and Mass Spectrometry (I (1.5 units)
ICP-ES/MS techniques are among the most powerful tools presently available for elemental analysis for a wide range of interests such as environmental, geological and biological applications. The fundamentals, state of the art instrumentation, applications, existing challenges, and new research and developments will be covered.
Course Component: Lecture
CHM 8358 Advanced Topics in Biomolecular Sciences (1.5 units)
Topics of current interest in biomolecular sciences and biological chemistry. Variable content from year to year. The course is equivalent to CHEM 5111 at Carleton University.
Course Component: Lecture
CHM 8359 Advanced Topics in Materials Chemistry (1.5 units)
Topics of current interest in Materials Chemistry. Variable content from year to year. This course is equivalent to CHEM 5112 at Carleton University.
Course Component: Lecture
CHM 8360 Characterization Methods and Applications of Advanced Materials. (1.5 units)
Detailed discussion of physico-chemical techniques from the practical and theoretical point of view. Topics covered will be chosen from the following: thermal analysis technics, optical spectroscopy, electrochemistry, X-ray and electron diffraction, electron microscopy, electron spectroscopies, magnetic resonance, and general instrumental methods. Applications related to materials science may include: field affect transistors, photovoltaics, light emitting devices, batteries, fuel cells, smart windows, and liquid crystalline displays. This course is equivalent to CHEM 5116 at Carleton University.
Course Component: Lecture
CHM 8361 Chemical Biology Part A (1.5 units)
Overview of the field of Chemical Biology focussed on modern aspects of molecular science with applications to understanding biological mechanisms. Concepts such as biorthogonal chemistry, chemical genetics, expanded genetic codes ans expanded genetic alphabets will be discussed in the context of how new chemical tools are developed and applied to understand and engineer living systems. Chemical probes for genomics, proteomics, metabolomics and vivo understanding of biology will be introduced with specific examples described. Genetically encoded probes will also be discussed. This course is equivalent to CHEM 5117 at Carleton University.
Course Component: Lecture
CHM 8362 Molecular Magnetism I (1.5 units)
Metal containing paramagnetic molecules are omnipresent in chemistry and biochemistry. The presence of unpaired electron in a system has a drastic effect on physical properties of a molecule. Provides an introduction to the principles (Molecular Magnetism I) and advanced characterization of paramagnetic molecules (Molecular Magnetism II). Emphasis will be made on structure property relationship. This course will contain variable content from year to year by discussing recent progress on molecular magnetism. This course is equivalent to CHEM 5119 at Carleton University.
Course Component: Lecture
CHM 8363 Chemical Biology Part B (1.5 units)
Overview of field of Chemical Biology focussed on modern aspects of molecular science with applications to understanding biological mechanisms. Concepts such as biorthogonal chemistry, chemical genetics, expanded genetic codes ans expanded genetic alphabets will be discussed in the context of how new chemical tools are developed and applied to understand and engineer living systems. Chemical probes for genomics, proteomics, metabolomics and vivo understanding of biology will be introduced with specific examples described. Genetically encoded probes will also be discussed. This course is equivalent to CHEM 5118 at Carleton University.
Course Component: Lecture
CHM 8364 Molecular Magnetism II (1.5 units)
Metal containing paramagnetic molecules are omnipresent in chemistry and biochemistry. The presence of unpaired electron in a system has a drastic effect on physical properties of a molecule. Provides an introduction to the principles (Molecular Magnetism I) and advanced characterization of paramagnetic molecules (Molecular Magnetism II). Emphasis will be made on structure property relationship. This course will contain variable content from year to year by discussing recent progress on molecular magnetism. This course is equivalent to CHEM 5121 at Carleton University.
Course Component: Lecture
CHM 8365 Communication in Chemistry (1.5 units)
This course will involve a variety of activities over the semester, including an oral presentation. The three major modes of scientific communication will be covered: written, verbal, and visual communication. Students will be educated in best practices via lectures and assignments, and regular attendance at Departmental seminars. Graded work will include: a) writing a cover letter and CV, and abstract for a conference presentation. b) communicating research orally to scientific and non-scientific audiences, c) producing a scientific poster. Plagiarism will also be discussed. The course is focused on students producing the above deliverables, peer review of their work, and enhancing student capacity to engage and communicate beyond a specialist academic audience.
Course Component: Lecture
CHM 8714 Électrochimie interfaciale (1.5 crédits)
Introduction aux processus électrochimiques. Double couche électrique. Transfert de charge. Théorie du transfert d'électrons, cinétique électrochimie et électrocatalyse.
Volet : Cours magistral
CHM 8722 Sujets choisis de la chimie de coordination (1.5 crédits)
Introduction des concepts fondamentaux de la chimie de coordination. Discussions des sujets suivants : fixation du dioxyde de carbone et de l'azote, activation, méthathèse d'oléfines, liaison métal-métal.
Volet : Cours magistral
CHM 8723 Méthodes de la mécanique quantique - théorie (1.5 crédits)
Description de la théorie sur laquelle sont basées les méthodes de chimie quantique (HF, MPS, CI, DFT).
Volet : Cours magistral
CHM 8958 Projet de recherche / Research Proposal
Préparation d'un projet de recherche, sans lien avec le sujet de la thèse, à présenter oralement devant un comité d'examen. La proposition écrite doit respecter les lignes directrices des Subventions à la Découverte du CRSNG. Les étudiants doivent démontrer leur capacité à défendre et à justifier le mérite scientifique, la méthodologie, l'importance et la nouveauté du projet. Les étudiants doivent s'inscrire et satisfaire à cette exigence au plus tard durant le 10e trimestre du programme de doctorat. Les étudiants qui échouent à cette activité peuvent se réinscrire une fois. / Preparation of a research project, unrelated to the thesis topic, to be defended orally before an examining committee. The written proposal should follow NSERC Discovery Grant guidelines. Students are required to demonstrate the ability to defend and justify the scientific merit, methodology, importance, and novelty of the project. Students must register and complete this requirement no later than term 10 of the PhD program. Students who fail this activity may repeat it only one time.
Volet / Course Component: Recherche / Research
CHM 9998 Examen général de doctorat / Ph.D. Comprehensive
Volet / Course Component: Recherche / Research
TOX 5129 Adverse Outcome Pathways: A Framework to Support the Modernization of Chemical Risk Assessment (3 units)
This course will introduce the Adverse Outcome Pathway (AOP) framework and how it can be used to support the integration of modern test methods (e.g. in silico, in vitro, high throughput, etc..) into the chemical risk assessment process. Students will first learn about current practices and recent advances in both human health and ecological chemical risk assessment. Then students will receive an advanced introduction to the AOP framework, including the theory of AOPs, how they can be used in regulatory toxicology for facilitating the use of mechanistic data, test paradigm development, and risk assessment, and training on best practices for contributing to the AOP knowledge base. This will include in-class case studies on AOP development and a final assignment where student will be responsible for developing a novel AOP for a specific toxicity.
Course Component: Lecture
TOX 8156 Principles of Toxicology (3 units)
The basic theorems of toxicology with examples of current research problems. The concepts of exposure, hazard and risk assessment will be defined and illustrated with experimental material from some of the more dynamic areas of modern research. This course is equivalent to BIOL 6402 at Carleton University.
Course Component: Lecture
TOX 8158 Environmental Chemistry and Toxicology (3 units)
Overview of environmental chemistry and toxicology principles including chemical sources, fate, and effects in the environment. Examining organic reactions occurring in abiotic environments and biological systems, study aspects of toxicant disposition and biotransformation. Emphasis on contemporary problems in human health and the environment.
Course Component: Lecture
TOX 9104 Ecotoxicology (3 units)
Selected topics and advances in ecotoxicology with emphasis on the biological effects of contaminants. The potential for biotic perturbance resulting from chronic and acute exposure of ecosystems to selected toxicants will be covered along with the methods pesticide, herbicide and pollutant residue analysis and the concept of bound residues. This course is equivalent to BIOL 6403 at Carleton University.
Course Component: Lecture
TOX 9105 Seminar in Toxicology (3 units)
A one-session course in seminar format highlighting current topics in toxicology. The student will present a seminar and submit a report on the seminar topic. Student, faculty and invited seminar speakers.
Course Component: Seminar
TOX 9106 Genetic Toxicology (3 units)
Topics in mutagenesis and DNA repair, including spontaneous and induced mutagenesis, genetic toxicology testing, the genetics and biochemistry of replication, DNA repair and recombination, and the role of mutagens in the development of genetic disease and cancer. This course is equivalent to BIOL 6406 at Carleton University.
Course Component: Lecture
TOX 9107 Toxicology and Regulation (3 units)
This course will help students develop the understanding and skills to apply research results in toxicology to real-world needs for the management of risks posed by environmental contaminants as well as the development of regulation and policy involving such management.
Course Component: Lecture